Synthetic opioids are man-made drugs designed to mimic the effects of natural opioids like morphine and codeine. These substances are often prescribed for pain relief but possess a significantly higher potency, which makes them a substantial risk for overdose. Chemically engineered in laboratories, these drugs can be altered to enhance their strength and effects. The risks associated with synthetic opioids are further compounded by the dangers of mislabeling and counterfeit products, which can lead to unintentional overdoses.
The potency of synthetic opioids is a double-edged sword. While they provide effective pain management, their high potency increases the risk of misuse and overdose. For instance, fentanyl is up to 100 times more potent than morphine, and carfentanil is even more dangerous, being about 10,000 times more potent than morphine.
The extreme potency of synthetic opioids means that even a small amount can have a significant impact on the body, leading to overdose. These drugs can quickly bind to opioid receptors in the brain, producing intense effects that can overwhelm the body’s systems. This high potency is compounded by their ability to cross the blood-brain barrier rapidly, increasing the risk of overdose. The lack of regulation and quality control in the production of these opioids further exacerbates the risk, as users may be unaware of the exact strength of the substances they are consuming.
Moreover, synthetic opioids are often mixed with other substances, making it difficult for users to know the exact potency of what they are consuming. This unpredictability significantly raises the risk of accidental overdose, especially when users are unaware of the drug’s strength or potential interactions with other substances.
Several factors contribute to the increased risk of overdose with synthetic opioids. Understanding these factors is crucial for prevention and harm reduction. One of the most dangerous synthetic opioids is carfentanil, known for its extreme potency and high risk of overdose.
People develop tolerance to opioids at different rates, which means a dose that feels manageable to one person may be lethal to another. Those with low or no opioid tolerance—such as new users or people in recovery—are especially vulnerable to overdose, even with small amounts.
Combining synthetic opioids with alcohol, benzodiazepines, or stimulants dramatically increases the risk of respiratory depression and overdose. These dangerous drug interactions can suppress vital functions like breathing and heart rate, often with fatal consequences.
A major contributor to overdose is misinformation or ignorance about the strength of synthetic opioids. Many users underestimate the potency of drugs like fentanyl or carfentanil, unknowingly consuming amounts that can cause immediate and deadly reactions.
Street drugs are often produced in unregulated labs without proper dosage control, leading to batches that vary wildly in strength. One pill may contain a survivable amount, while the next may have a lethal dose—making illicit synthetic opioids especially hazardous.
Synthetic opioids like fentanyl have extremely high bioavailability, meaning they enter the bloodstream and affect the brain rapidly. This quick onset intensifies their effects and shortens the window for medical intervention in case of an overdose.
Recognizing the signs of a synthetic opioid overdose is critical for timely intervention. Overdose symptoms can escalate rapidly, and immediate action is necessary to prevent fatal outcomes. Common signs of a synthetic opioid overdose include:
Prevention and management of synthetic opioid overdose require a multi-faceted approach, including education, harm reduction strategies, and emergency interventions. Avoiding risky behaviors is essential in reducing the likelihood of overdose, as it involves understanding the dangers and making informed decisions.
Key measures to prevent and manage overdose include:
Understanding the importance of avoiding risky behaviors is crucial in reducing the likelihood of overdose. Making informed decisions and being aware of the dangers associated with synthetic opioids can save lives.
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Nika has been practicing in the mental health field and in substance abuse as a licensed psychotherapist for over 20 years with the emphasis of applying psycho-dynamic theories to better understand attachment styles, trauma, and the unconscious forces that can play in one’s current behaviors, thoughts and emotions leading to addictions and other maladaptive behaviors.
Nika believes awareness of the root cause of our problems alone may not bring about the changes one is desiring. She believes that in addition to the psychodynamics, when a client learns how to deal with their painful feelings instead of creating defense mechanisms for it then fear is no longer the dominant factor. It is then when you begin to value yourself enough to change. To understand and challenge thinking patterns and valuing the capacity, skills, knowledge, connections, and potentials of each individual with compassion, empathy and interest through how they experience difficulties creates trust.
Nika believes when trust is established anything is possible and the strategies that are implemented work effectively “ without the compassion, empathy and the ability for the client to be heard and understood there should be no expectation for a client to talk about layers of trauma that they have tucked away for good reason”.
The ability to look beyond their presenting problems, childhood experiences and making the incremental changes needed in creating the life they intended to live is possible.
Nika also works in her private practice and has achieved academic publishing and Author of Unveiling Iranian women’s beliefs and attitudes towards divorce, published through Lambert Academic Publishing.